Quantitation of the Chiral Shift in Metabolism of Propranolol Using 2D-LC/MS/MS

Investigating the Chiral Metabolism of an Achiral Drug Using Agilent SFC‑MS/MS Technology Application Note Pharma Discovery Authors Abstract Siji Joseph A robust SFC-MS/MS method was developed for the quantification of achiral Agilent Technologies, Inc. risperidone and its enantiomeric hydroxy metabolite.…

Application Note Environmental Direct Injection and Online SPE LC/MS/MS for the Determination of Pharmaceuticals and Personal Care Products (PPCPs) in Water Samples Using the Agilent InfinityLab Online SPE Solution Authors Gerd Vanhoenacker and Koen Sandra Research Institute for Chromatography President…

Application Note Pharma & Biopharma Simultaneous Impurity Analysis and Enantioseparation of Atenolol Using Achiral-Chiral 2D-LC Author Lucas Willmann Agilent Technologies, Inc. Abstract To ensure the quality of drug products, chromatographic separation of synthetic byproducts from active pharmaceutical ingredients (APIs), as…

[ ACQUIT Y UPC 2 COLUMNS ] ACQUITY UPC 2 Columns for chiral and achiral separations ACQUITY UPC2 COLUMNS ACQUITY UPC2 Instruments and Columns The ACQUITY UPC 2® System gives scientists the ability to precisely vary mobile phase strength, pressure,…