Use of a MAbPac RP capillary column to monitor glycosylation site occupancy in therapeutics

Disulfide Bond and Glycosylation Site Occupancy Mapping of Trastuzumab Using a Novel Capillary MAbPac RP Column Zoltan Szabo1, Xuefei Sun1, Brandon Robson1, Mike Baynham2 and Shanhua Lin1 1Thermo Fisher Scientific, Sunnyvale, USA, 2Thermo Fisher Scientific, Runcorn, UK ABSTRACT RESULTS Purpose:…

APPLICATION NOTE 21835 An automated high-throughput workflow for peptide mapping to monitor post-translational modifications (PTMs) of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Giorgio Oliviero, Sara Carillo, Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing…

APPLICATION NOTE 21781 Investigating process-related post-translational modifications in NISTmAb RM 8671 using high-throughput peptide mapping analysis Authors Silvia Millán, Craig Jakes, Noemí Dorival, Sara Carillo, Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and…

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