Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury Mice Using GCxGC-TOFMS with Data Analysis Using a Software Driven Reference Feature

GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study John Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USA INTRODUCTION METHODS Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry has…

Blood Serum Metabolomics Using Comprehensive Two-Dimensional Gas Chromatography High Resolution Time-of-Flight Mass Spectromery David E. Alonso, Joe Binkley, Lorne Fell, and Christina Kelly | LECO Corporation, St. Joseph, MI 10,11 17-19 Time (s) 400 600 800 1000 37 39,40 38…

Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma John Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USA OBJECTIVES Demonstrate the enhanced detection and increased peak…

Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma John Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USA OBJECTIVES Demonstrate the enhanced detection and increased peak…