Utilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological Samples

® Small Molecule Metabolite Identifications in Diabetic Versus Non-Diabetic Urine Sample Groups Using Comprehensive Two-Dimensional Gas Chromatography Combined with Time-of-Flight Mass Spectrometry (GCxGC-TOFMS) John Heim, LECO Corporation; Saint Joseph, Michigan USA Key Words: Fisher Ratio, Sample Groups, Diabetes, Metabolite Profile…

® Delivering the Right Results GCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic and Non-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate Analysis John R. Heim, Scott Pugh, and Mark Libardoni • LECO Corporation, St. Joseph, Michigan OVERVIEW EXPERIMENTAL METHODS…

® Utilization of Statistical Compare Software and Fisher Ratios Prior to Multivariate Analysis for Complex GCxGCTOFMS Data in Order to Define Statistical Variation Between the Small Molecule Metabolite Profiles of Different Fish Species John Heim • LECO Corporation; Saint Joseph,…

GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study John Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USA INTRODUCTION METHODS Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry has…