Rapid Determination of Drug Protein Binding Affinity using Solid Phase Microextraction

Investigation of Solid Phase Microextraction as an Alternative to Dried Blood Spot Craig Aurand and Robert Shirey Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA sigma-aldrich.com/analytical T414068 © 2014 Sigma-Aldrich Co. All rights reserved. Introduction • There has been a…

Application Note Ultrafast Plasma Protein Binding Analysis Using the Agilent RapidFire high-throughput mass spectrometry system and accurate mass Q-TOF Authors Abstract Kari E. Schlicht and Vaughn P. Miller Agilent Technologies, Inc. There has been increased demand for higher throughput in…

Direct Analysis of Drug of Abuse by BioSPME Craig Aurand, Robert Shirey, and Len Sidisky Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA sigma-aldrich.com/analytical T415080 © 2015 Sigma-Aldrich Co. All rights reserved. Introduction Urine testing for the presence of drugs…

LC/MS/MS Analysis of Fentanyl and Related Analogs Using Biocompatible Solid Phase Microextraction Petra Lewits1, Emily Barrey2, Cory E. Muraco3 Merck KGaA Darmstadt, Germany 1Applied Solutions Advanced Analytical, Frankfurter Strasse 250, 64239 Darmstadt, Germany, Global Product Manager HPLC columns 2Sample Preparation…