Characterization of the Interactions Between High Mannose Glycans and a Novel Prokaryotic Lectin Using Mass Spectrometry-Based Approaches

No. SSI-LCMS-116 Liquid Chromatography Mass Spectrometry No. LCMS-116 N-Linked Glycans Analysis of Monoclonal Antibodies, Biosimilars, and Glycoproteins with High Resolution Mass Spectrometry and Fluorescence Detection using Restek’s Raptor Polar X Column and Protein Metrics’ Software Suite ■ Introduction Therapeutic antibodies…

Developing High Resolution HILIC Separations of Intact Glycosylated Proteins Using a Wide-Pore Amide-Bonded Stationary Phase Matthew A. Lauber, Scott A. McCall, Bonnie A. Alden, Pamela C. Iraneta, and Stephan M. Koza Waters Corporation, Milford, MA, USA A P P L…

Application Note Pharma & Biopharma A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS Author Brian Liau Agilent Technologies, Inc. Introduction Recent years have witnessed a rapid increase in the…

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…