Modernization of a Legacy Normal-Phase HPLC Method

MODERNIZATION OF A LEGACY NORMAL PHASE METHOD ON A MODERN HPLC SYSTEM E. Pedanou, L. Gauthier, and P. Hong Waters Corporation, Milford, MA, USA INTRODUCTION METHOD RESULTS & DISCUSSION RESULTS & DISCUSSION In regulated laboratories, particularly those within the pharmaceutical…

Application Note Hydrophilic Interaction Liquid Chromatography (HILIC) Method Migration Part 1: From Legacy HPLC Systems to the Alliance™ iS HPLC System Elom Y Pedanou, Paula Hong, Neil J. Lander Waters Corporation Abstract This application note helps illustrate a successful hydrophilic…

Application Note Modernizing Compendial SEC Methods for Biotherapeutics Using the Alliance™ iS Bio HPLC System Pawel Bigos, Robert E. Birdsall, Karen Nyholm Waters Corporation Abstract The process of method modernization, which involves integrating advancements in system and column technology for…

[ APPLICATION NOTE ] USP Analysis of Glimepiride on an Alliance HPLC System: Modernization of a USP Method Aaron D. Phoebe, Paula Hong, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Alliance system flexibility enables…