Rapid Quantitation of Quaternary Amine Surfactants by UHPLC‐C

D. Foley, W. Faulkner, Thermo Fisher Scientific, Runcorn, Cheshire, UK Key Words Acclaim Surfactant Plus, cationic surfactants, mixed mode chromatography, selectivity Abstract The simultaneous separation of a range of cationic surfactants using a highly selective and robust Thermo Scientific Acclaim…

Charged Aerosol Detection 101 Dr. Alexander Schwahn European Sales Support Expert for Biopharma Industry Thermo Fisher Scientific, Reinach, Switzerland The world leader in serving science Outline • • • • • • 2 Introduction to charged aerosol detection (CAD) How…

Table of contents Summary Overview Excipient function Measurement Charged Aerosol Detector Universal detection Uniform response Working principles (U)HPLC Systems with CAD Columns choice Excipients overview Adjuvants Amino acids Carbohydrates Counterions Nonionic surfactants Polyethylene glycol Proteins and excipients HPLC-Charged Aerosol Detection…

Application note | 000465 UHPLC-CAD Characterization of lipid nanoparticle (LNP) composition using UHPLC-CAD Authors Application benefits Sissi White1, Ken Cook 2, Mark Netsch3, • Simple UHPLC method for characterization of the lipid components of LNPs • Universal response shows relative…