IMSC: MALDI Imaging of Metabolites Reconstructed by CE-MS Based Quantitative Analysis

Metabolite maps reconstructed using a quantitative data by capillary electrophoresis-mass spectrometry (CE-MS) ASMS 2012 MP15-346 Tsuyoshi Nakanishi 1, Takako Hishiki 2, Shigeki Kajihara 3, Kiyoshi Ogawa 3 and Makoto Suematsu 2, 4 1 MS Business Unit, Shimadzu Corporation, Kyoto, Japan…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

Tracking free-toxin distribution in xenografts after in-vivo ADC dosing by MALDI Imaging MALDI-MRMS imaging of free released toxin in xenografts after ADC in-vivo dosing. Abstract Antibody-drug conjugates (ADC), a fast-growing class of anticancer drugs, typically comprise a cytotoxic payload that…

Application note | 003509 Metabolomics Advancing spatial lipidomics: high spatial resolution mass spectral imaging (MSI) using the MassTech AP-MALDI UHR ion source with the Orbitrap Exploris mass spectrometer Authors Application benefits Maureen Feucherolles , Gilles Frache , 1 1 •…