Characterizing the Electrophoretic Mobility, Charge, And Zeta Potential of Biopolymers

Light Scattering for the Masses © Möbiuζ Computation of Protein Net Charge from Electrophoretic Mobility he Möbiuζ measures the mobility (electrophoretic) of macromolecules by means of Phase Analysis Light Scattering (PALS). In addition to a protein’s mobility, most researchers are…

Characterizing Dendrimers by Asymmetric Flow Field Flow Fractionation Sigrid C. Kuebler, Aym M. Berges, Vivianna C. Lim, Wyatt Technology Corporation, 6300 Hollister Ave, Santa Barbara, CA 93117 Why look at Dendrimers? Ethylenediamine‐core poly(amidoamine) (PAMAM) Dendrimers • Dendrimers have a high…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…

Analytical techniques for determining monoclonal antibody charge Dana I. Filoti*, Susan F. Chase*, John C. Champagne** and Thomas M. Laue* *University of New Hampshire, Durham NH **Wyatt Technology Corporation, Santa Barbara CA BITC CAMIS We have examined the electrophoretic mobility…