Stoichiometry of Lysin Holoenzyme

WP1621: Multi-Attribute Quantitation of Antibody-Drug Conjugates by LC-MALS Hongjiang (Leo) Liu, Ph.D., and Sophia Kenrick, Ph.D., Wyatt Technology, LLC Summary Liquid chromatography combined with multi-angle light scattering (LC-MALS) is a powerful tool for analyzing antibody-drug conjugates (ADCs), providing a robust…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…

I TEE PPAAPPEERR WWHHI T WP1615: SEC-MALS for absolute biophysical characterization Daniel Some, Ph.D., Waters | Wyatt Technology Summary Accurate characterization of biomacromolecules is essential for successful programs of research and development in the life sciences and biopharmaceuticals. The basic…

W H I T E PA P E R WP3001: SEC-MALS and CG-MALS: Complementary Techniques to Characterize Protein-DNA Complexes Sophia Kenrick, Ph.D., Waters | Wyatt Technology Summary Interactions between proteins and nucleic acids often result in binding stoichiometries greater than…