Automated, Online Second Virial Coefficient (A2) Measurements

Calypso Application Note: Automated 2nd virial coefficients with Calypso The 2nd virial coefficient (A2) is a general measure of weak, non‐specific protein‐ protein interactions. Characterization of A2 vs. buffer properties, e.g. ionic strength or pH, is useful in optimizing a…

A P P L I C AT I O N N O T E AN3009: Characterization of self-associating antibody solutions at high concentrations with CG-MALS Sophia Kenrick, Ph.D. and Daniel Some, Ph.D., Waters | Wyatt Technology Summary The characterization of…

Protein Solutions™ Rapid, Automated Molecular Characterization Using a Binary HPLC pump A standard binary pump, such as those used for HPLC systems, may be used to prepare, mix, and inject multiple sample concentrations required for a standard Zimm plot. Continuous…

Light Scattering for the Masses ® Rapid, Autonomous Lot-to-Lot Comparability of Monoclonal Antibodies with the Calypso nalysis of purity and demonstration of lot to lot comparability is essential throughout the drug development process. Among the various biophysical and biochemical assessments…