Reducing the Complexity of Polysorbate Oxidation By-Product Screening by LC/MS/MS

Poster Reprint ASMS 2025 Poster number ThP 752 Comprehensive Investigation of Polymer Oxidation using Interactive Visualizations and User Modified Libraries in PolyMatch Suite Wendi A Hale1; Jeremy P Koelmel2; Nicholas Oranzi3; David Weil4; Emma E. Rennie4; Paul Stelben2; Michael Kummer5;…

Non-targeted analysis, interactive visualization, and online sharing of interactive LC-HRMS/MS data of polymers using a comprehensive software PolyMatch Suite Introduction Jeremy Koelmel [1]; David A Weil [2]; Emma E. Rennie* [2]; Paul Stelben [1]; Nicholas Oranzi [3]; Michael Kummer [4];…

APPLICATION NOTE 73979 Polysorbate 80 profiling by HPLC with mass and charged aerosol detection Authors: Mauro De Pra, Denis A. Ispan, Katherine Lovejoy, Sylvia Grosse, Stephan Meding, Frank Steiner Thermo Fisher Scientific, Germering, Germany Keywords: Vanquish Flex, Vanquish Duo, ISQ…

Simultaneous analysis of polysorbate 80 and poloxamer 188 in biopharmaceutical formulations using charged aerosol detector and single quadrupole mass spectrometer Xuepu Li 1, Sissi White 2, Mauro De Pra 3, Yu Cui 1, Min Du 2 1Thermo Fisher Scientific, Shanghai,…