Shining Light on Polysorbate Hydrolysis by LC/ELSD

Consumables workflow ordering guide Polysorbate Degradation Analysis with the AdvanceBio Surfactant Profiling HPLC Column Introduction Polysorbates are ubiquitous ingredients in healthcare products, from eye drops and cough syrups to mouthwash and sunscreen. Polysorbates act as emulsifiers, solubilizers, surfactants, and stabilizers…

Agilent AdvanceBio Surfactant Profiling HPLC columns In-depth characterization of surfactant and surfactant degradation in biotherapeutic applications Surfactants: Balancing the Benefits and Risks Surfactants are a vital component of biologic formulation buffers, preventing biologic aggregation and adsorption at the air-liquid interface.…

Application Note Biopharma Separation and Analysis of Polysorbate 80 in the Presence of Human Serum Immunoglobulin G Using Agilent Bond Elut Lipid Extraction SPE Cartridges Authors Sanjeewa N. Senadheera, Limian Zhao, and Derick Lucas Agilent Technologies, Inc. Abstract Protein aggregation…

QUALITY ASSESSMENT OF POLYSORBATES 80 AND 20 PHARMACEUTICAL RAW MATERIALS BY MEASURING FATTY ACIDS COMPOSITION USING HPLC WITH MASS DETECTION Authors: Margaret Maziarz, Paul Rainville, Isabelle VuTrieu, Andrew Leightner Affiliations: Waters Corporation, Milford, MA The U.S. Pharmacopoeia specifies a gas…