High-throughput 96-well cocrystal screening workflow for active pharmaceutical ingredients

Application Note An automated, high-throughput approach to generating cocrystals with solvent-drop grinding (SDG) Introduction would enable exploration of a much broader experimental space. In this appli­cation note, we describe the development of an automated high‑throughput method for cocrystal screening with…

Application Note High-throughput polymorph screening of active pharmaceutical ingredients Introduction Powerful software to design, execute and analyze data from polymorph screens Many active pharmaceutical ingredients (API) exhibit polymorphism. Since each polymorph can exhibit different properties, such as solubility and bioavailability,…

Sigma-Aldrich Integrated Chiral Services • Paul Rodwell and Thierry Bonnaud Chirality 2012 Fort Worth, Texas, 10th-13th June Agenda • • • • • • • • Introduction Sigma-Aldrich Integrated Chiral Services Capability SAFC Pharmorphix® Chiral Services Overview Chiral Method Development…

Small Molecule Preformulation Kick your preformulation screening into high gear Big Kahuna systems give you automated, high-throughput, end-to-end solutions to characterize every last physicochemical property of your drug candidates. They’re completely configurable and built to take on the hard stuff.…