Coupling ion exchange chromatography with mass spectrometry to characterize charge heterogeneity of mAbs under near-native conditions using a ProPac 3R SCX column

BioLC columns Connected chromatography solutions BioLC columns and accessories Introduction Your complete tool kit Thermo Fisher Scientific has innovative Thermo Scientific™ BioLC columns for each step of your therapeutic protein characterization, no matter how challenging your separation. Here is just…

Application note | 003310 Biopharma Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS Authors Application benefits Maria Grübner , Kai Scheffler , 1 1 • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of…

Application note | 001695 Biopharma Salt gradient analysis of Protein G using a 3 μm monodisperse SAX chromatography column Authors Application benefits Ke Ma, Shane Bechler • High-resolution separation of protein charge variants • Easy, straightforward method development • Consistent…

3µm Monodisperse IEX Media 3µm monodisperse particles for Ion Exchange Chromatography stationary phases and their impact on the separation of biomolecules S. Bechler , K. Ma, R. Olivares, R. Cowley, Y. Hu, Y. Singh, and S. Lin, Thermo Fisher Scientific,…