Immunopeptidomics: Harnessing cutting-edge technology for unprecedented depth and accessibility in analysis to leverage the immune response for precision therapy

Technical note | 003923 Omics Unlocking the immunopeptidome High-sensitivity and accurate mass spectrometry with the Orbitrap Astral Zoom mass spectrometer for superior antigen characterization Authors Goal Fernanda Salvato1, Nicholas Cheung2, To assess depth and quality of immunopeptidome coverage using data-dependent…

Orbitrap MS Leveraging advanced mass spectrometry technology with Orbitrap Astral Zoom MS for in depth immunopeptidome profiling Fernanda Salvato1, Nicholas Cheung2, Robert Salzler2, Ellen Casavant1,Tonya Pekar Hart1, Amirmansoor Hakimi1. 1Thermo Fisher Scientific, San Jose, CA, USA, 2Regeneron Pharmaceuticals, Tarrytown, NY,…

P-III-1101 Orbitrap Astral MS Enhancing Immunopeptide Profiling with Orbitrap Astral Mass Spectrometer for Unbiased Discovery of Neoantigens Fernanda Salvato, Lilian Heil, Ellen Casavant, Amirmansoor Hakimi, Tonya Pekar Hart Thermo Fisher Scientific, San Jose, CA, USA Abstract Figure 2. Experimental workflow…

Technical note | 003570 Proteomics Unprecedented depth and data quality in immunopeptidome profiling with the Orbitrap Astral mass spectrometer Authors Goal Fernanda Salvato, Lilian Heil, To assess depth and quality of immunopeptidome coverage using data-dependent Ellen Casavant, Tonya Pekar Hart,…