Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak™ High Performance Surface Technology

M1030-01-01 Development of Improved Chromatographic Methods for the Separation of Synthetic Peptides Medications and Associated Impurities Paul Rainville, Brianna Clements, and Adam Bengtson Waters Corporation 34 Maple Street Milford MA 01757 USA CONTACT INFORMATION: [email protected]. PURPOSE Glucagon-Like Peptide-1 agonists (GLP-1s)…

Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology XSelect Premier 0.40 0.130 0.00 9.00 0.120 AU 0.06 0.04 21.50 0.100 0.090 0.080 0.070 0.060 0.050 0.040 21.60 21.70 21.80 21.90…

Application Note Method Development for the Chromatographic Separation of Synthetic Cyclic Peptides and Impurities Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology Adam Bengtson, Paul D. Rainville, Stephanie Harden Waters Corporation Abstract Waters has developed a systematic protocol,…

Application Note Leveraging the Alliance™ iS Bio HPLC System as a Modern HPLC for Peptide Drug Substances Analysis in QC Environments Duanduan Han, Robert E. Birdsall, Karen Nyholm Waters Corporation Abstract The Alliance iS Bio HPLC System with MaxPeak™ High…