Improved LC/MS Performance to Determine Polar Nitrosamines Using the Agilent 1260 Infinity II Hybrid Multisampler

Application Note Pharmaceutical Determination of Nitrosamines in Active Pharmaceutical Ingredients High flexibility and performance at lowest cost using the Agilent 1260 Infinity II Prime LC with the Agilent Ultivo LC/TQ for LC/MS analysis Author Edgar Naegele Agilent Technologies, Inc. Abstract…

Application Note Biopharma Quantitative Analysis of Nitrosamine Impurities in Synthetic Oligonucleotides Using the Agilent 6495D triple quadrupole LC/MS system Author Abstract Yulan Bian Agilent Technologies, Inc. Nitrosamines are genotoxic impurities of significant concern in pharmaceuticals due to their carcinogenic potential.…

Application note | 001657 Pharma Highly sensitive and robust LC-HRAM-MS method for simultaneous quantitation of sixteen nitrosamines in multiple drug products Goal Authors Krishna Mane , Venkatesh Chanukuppa , The aim of this study was to evaluate and report on…

Stanovení nitrosaminů v uzeninách Simona Wawroszová Senior Application Chemist Nitrosaminy: Vznik a výskyt v masných výrobcích ▪ Nitrosaminy vznikají reakcí dusitanů a dusičnanů (používaných jako konzervanty) s aminy ▪ K tvorbě dochází za kyselých podmínek, při tepelném zpracování (pečení, smažení)…