5 Rules of Scaling LC Purification - Rule #3: Always be consistent with column volumes

[ ARTICLE ] 5 Rules of Scaling LC Purification Rule #1: Scale flow rate and sample load proportionately Author: Jo-Ann Jablonski, Principal Scientist, Waters Corporation Chemists have been diligent in their pursuit to uncover best practices for achieving more reliable…

Application Solutions For P re parat iv e-Scal e C hromatogra phy APPLICATION SOLUTIONS FOR PREPARATIVE-SCALE CHROMATOGRAPHY 4 Introduction 5 UV-Directed Purification of a Small-Scale Organic Synthesis 9 Preparatory Chromatography of Natural Product Extracts Utilizing a UV-Based Open Access Walk-Up…

[ ARTICLE ] 5 Rules of Scaling LC Purification Rule #4: Leverage identical column attributes and similar LDP Author: Jo-Ann Jablonski, Principal Scientist, Waters Corporation LC Column attributes may include several column specifications that a manufacturer provides for a given…

[ APPLICATION NOTE ] Antioxidant Isolation Using the Prep 150 LC System Catharine Layton and Andy Aubin Waters Corporation, Milford, MA, USA TECHNOLOGY BENEFITS ■■ ■■ ■■ INTRODUCTION The Waters® Prep 150 LC System, Compounds and extracts isolated from natural…