Discovery lipidomics study for colorectal cancer using a Xevo™ MRT Mass Spectrometer and Lipostar data processing workflow

COMPREHENSIVE DISCOVERY LIPIDOMIC WORKFLOW WHICH UTILIZES A NOVEL, MULTI-REFLECTING TOF WITH INTEGRATED INFORMATICS, PROVIDING HIGHLY CONFIDENT LIPID CHARACTERIZATION AND QUANTIFICATION Nyasha Munjoma 1 , Hirose Kenji 2 , Laura Goracci 3 , Paolo Tiberi 4 , Jayne Kirk 1 ,…

[ PRODUCT SOLUTION ] A High-Throughput Lipodomic Workflow Using the Waters Xevo MRT Mass Spectrometer INTRODUCTION The Xevo™ MRT Mass Spectrometer delivers an unrivaled combination of performance at speed, providing high resolution time-of-flight data independent of spectral EXPERIMENTAL CONDITIONS SAMPLES…

[ PRODUCT SOLUTION ] Employing ballistic gradients, vacuum jacketed columns and prototype benchtop multi reflecting time-of-flight (MRT) to increase lipidomic throughput whilst maintaining highly confident identifications Authors: Matthew E. Daly 1, Nyasha Munjoma1, Rob S. Plumb2 , Jason Hill2 ,…

COMPARISON OF FAST SCANNING DATA DEPENDENT AND DATA INDEPENDENT ACQUISITION METHODS FOR A MULTI-OMIC CANCER STUDY USING HIGH-SPEED CHROMATOGRAPHY Lee A. Gethings1, Matthew Daly1, Martin Palmer1, Richard Lock1, Jason Wildgoose1, James I. Langridge1 1 Waters Corp., Wilmslow, Cheshire, United Kingdom…