Flash Characterization of mAbs Using a Combination of Reagents via Automated On-Line Microdroplet Reaction

Poster Reprint ASMS 2023 Poster number MP 616 “Flash Characterization” of Antibodies via Microdroplet Reactions in an Unmodified Jet Stream Source Jim Lau1, Mike Knierman1, Hui Zhao1, Harsha Gunawardena2 1Agilent Technologies, Inc. Santa Clara, CA 2Janssen Research & Development, Johnson…

Application Note Biopharma Flash Characterization of Antibodies via Microdroplet Reactions in an Unmodified Jet Stream Source Authors Introduction Jim Lau, Hui Zhao, and Mike Knierman Agilent Technologies, Inc. Traditionally, antibody characterization with IdeS enzyme digestion, reduction with tris(2-carboxyethyl)phosphine (TCEP), triethylphosphine…

Poster Reprint ASMS 2024 Poster number MP 645 Combining Microdroplet Reactions with ExD Fragmentation for Fast Characterization of Proteins and Antibody Subunits Thomas E Walker1; Rachel Franklin2; Joseph Meeuwsen2; Jim Lau3 1Agilent Technologies, Lexington, MA 2Agilent Technologies, Corvallis, Oregon 3Agilent…

Technical Overview Ultrafast Antibody Peptide Mapping with the Agilent 6545XT AdvanceBio LC/Q-TOF Authors Introduction Mengyuan Xiao, Yongqing Yang, Andrew Schladebeck, and Hao Chen Department of Chemistry & Environmental Science, New Jersey Institute of Technology, Newark, NJ, 07102, USA This technical…