Evaluation binding of individual and combined domains in the bacterial flagellar motor complex by CG-MALS

Application Note Wyatt Technology Corporation 9L]LHSPUN[OL(MÄUP[`VM Individual and Combined FliG Domains for FliM in the Bacterial Flagellar Motor Complex Summary Complex interactions between proteins modulate the rotational direction of bacterial flagella. In particular, the middle and C-terminal domains of FliG…

Light Scattering for the Masses ® Measuring the Interaction Between Thrombin-α and an Anti-Thrombin Antibody Summary Antibody-antigen binding, hormone-receptor interactions, and many other common biomolecular interactions occur at stoichiometries other than 1:1. The Wyatt Calypso system utilizes composition-gradient multi-angle light…

W H I T E PA P E R WP3001: SEC-MALS and CG-MALS: Complementary Techniques to Characterize Protein-DNA Complexes Sophia Kenrick, Ph.D., Waters | Wyatt Technology Summary Interactions between proteins and nucleic acids often result in binding stoichiometries greater than…

Light Scattering for the Masses ® Binding Affinity and Stoichiometry of a Multivalent Protein-aptamer Association Summary ecause proteins are often multimeric in their native state, the biomarker targets of many pharmaceuticals present multiple binding sites. In the case of monoclonal…