Identification of insulin oligomeric states using SEC-MALS

I TEE PPAAPPEERR WWHHI T WP1615: SEC-MALS for absolute biophysical characterization Daniel Some, Ph.D., Waters | Wyatt Technology Summary Accurate characterization of biomacromolecules is essential for successful programs of research and development in the life sciences and biopharmaceuticals. The basic…

AN3004: Self-association of insulin quantified by CG-MALS Vijay Pandyarajan, M.D., Ph.D.1, Nelson B. Phillips, Ph.D.1, Sophia Kenrick, Ph.D.2, Michael A. Weiss, Ph.D.1 1Case Western Reserve University 2Wyatt Technology Corp. Summary Therapeutic insulin analogs, engineered for specific states of self-association, have…

AN3002: Understanding antibody and viral glycoprotein interactions using CG-MALS Kathryn M. Hastie, Ph.D., and Erica Ollmann Saphire, Ph.D., The Scripps Research Institute Summary Viral glycoproteins are often the only antigen found on the viral surface and, as such, are key…

W H I T E PA P E R WP3001: SEC-MALS and CG-MALS: Complementary Techniques to Characterize Protein-DNA Complexes Sophia Kenrick, Ph.D., Waters | Wyatt Technology Summary Interactions between proteins and nucleic acids often result in binding stoichiometries greater than…