Creating Greener HPLC Methods as Measured by the AMGS Metric: A Case Study of Improving USP Monograph Methods

Application Note Applying Analytical Method Greenness Scoring to the USP Monograph of Naproxen; Improving the Sustainability of Validated Methods by Modernizing to Newer Technology Kenneth D. Berthelette, Thomas H. Walter, Chris Collins, Maureen DeLoffi, Kim Haynes Waters Corporation This is…

Application Note Improving Sample Throughput of HPLC Methods Using CORTECS 5 µm Columns Kenneth Berthelette, Maureen DeLoffi, Thomas H Walter Waters Corporation, United States Published on October 28, 2025 Abstract Validated HPLC methods are prime targets for systematic improvements like…

Application Note Improving Throughput and Analytical Greenness in Pharmaceutical Discovery Using Ultrashort (2.1 x 10 mm) HPLC Columns Kenneth Berthelette, Christopher Collins, Thomas H Walter Waters Corporation, United States Published on October 14, 2025 Abstract High-throughput is critical for analytical…

Application Note Taking Advantage of 12k psi Pressure Capabilities for Modernizing USP Methods on the Alliance™ iS HPLC System Amanda B. Dlugasch, Paula Hong Waters Corporation, United States Published on August 19, 2025 Abstract Pharmaceutical companies frequently use compendial high…