RPC-MALS analysis of protein oligomers

Multi-Angle Light Scattering goes micro Dr. Dierk Roessner International Symposium on GPC/SEC and Related Techniques Frankfurt 2014 © 2014 Wyatt Technology Europe GmbH - All Rights reserved Page 1 Overview Why use Multi Angle Light Scattering ? Challenges coupling UV…

I TEE PPAAPPEERR WWHHI T WP1615: SEC-MALS for absolute biophysical characterization Daniel Some, Ph.D., Waters | Wyatt Technology Summary Accurate characterization of biomacromolecules is essential for successful programs of research and development in the life sciences and biopharmaceuticals. The basic…

AN1611: High-Speed Process Monitoring with UHP-SEC-MALS Sophia Kenrick, Wyatt Technology Corp. Summary Introduction Size exclusion chromatography (SEC) is widely used for detecting aggregates, fragments, and other impurities in a biotherapeutic sample. When coupled with multi-angle light scattering (MALS), SEC enables…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…