IEX-MALS - a method for protein separation and characterization

I TEE PPAAPPEERR WWHHI T WP1615: SEC-MALS for absolute biophysical characterization Daniel Some, Ph.D., Waters | Wyatt Technology Summary Accurate characterization of biomacromolecules is essential for successful programs of research and development in the life sciences and biopharmaceuticals. The basic…

AN1611: High-Speed Process Monitoring with UHP-SEC-MALS Sophia Kenrick, Wyatt Technology Corp. Summary Introduction Size exclusion chromatography (SEC) is widely used for detecting aggregates, fragments, and other impurities in a biotherapeutic sample. When coupled with multi-angle light scattering (MALS), SEC enables…

AN8004: Coupling MALS with preparative ionic-exchange (pIEX) for structural biology applications Sandro Vivona, Ph.D., AbbVie Inc. Summary Ion-exchange chromatography is a common intermediate step in a protein purification protocol. Adding multi-angle light scattering in-line to preparative ion-exchange chromatography (pIEX-MALS) allows…

2015 International Symposium on GPC/SEC and Related Techniques The Sun Rises Over UHP‐SEC: µDAWN for Polymer Characterization by MALS WWW.WYATT.COM © Wyatt Technology Corporation – All Rights Reserved Why UHP‐SEC? • aka: UHPLC‐SEC, SE‐UHPLC, APC (SEC using 1.7 to 2.5…