Analysis of mRNA-Lipid Nanoparticles in Human Plasma using SEC-Static Dual-Angle Light Scattering and Refractive Index Detection

Application Note Biopharma Advanced SEC with Online LS/DLS Detection for the Analysis of Lipid Nanoparticles CQAs Authors Johanna Simon and Jenny Hong-Hoang Merck Life Science KGaA, Darmstadt, Germany Sonja Schneider Agilent Technologies, Waldbronn, Germany Abstract The size of lipid nanoparticles…

Enhance Biopharma Insights with Advanced Size Exclusion Chromatography Agilent Biopharma SEC Solutions 2 3 Size exclusion chromatography (SEC) plays an essential role in the analysis of biopharmaceutical modalities like monoclonal antibodies, viral vectors, mRNA, and other. SEC enables the determination…

W H I T E PA P E R WP9007: Characterizing vaccines with light scattering Camille Lawrence, Ph.D., Waters | Wyatt Technology Introduction Vaccines are an indispensable weapon in the fight against human and animal disease, and countless lives have…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…