EAS: Systematic Protocol Utilizing High Performance Surface Technology for the Improved Separation and Quantification of Synthetic Peptides and Associated Impurities

Application Note Method Development for the Chromatographic Separation of Synthetic Cyclic Peptides and Impurities Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology Adam Bengtson, Paul D. Rainville, Stephanie Harden Waters Corporation Abstract Waters has developed a systematic protocol,…

Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology XSelect Premier 0.40 0.130 0.00 9.00 0.120 AU 0.06 0.04 21.50 0.100 0.090 0.080 0.070 0.060 0.050 0.040 21.60 21.70 21.80 21.90…

Application Note Analytical Quality by Design Method Development and Optimization of an Impurity Profiling Method for GLP-1 Receptor Agonist Exenatide Pawel Bigos, Robert E. Birdsall, Duanduan Han, Karen Nyholm Waters Corporation, United-States Published on March 06, 2025 Abstract An analytical…

MaxPeak Premier Columns Small Molecule Application Notebook CONTENTS Introduction Non-Specific Adsorption: Unwanted Interactions................................................................................... 3 How Do Scientists Solve This Problem Today?......................................................................................... 4 Precision Chemistry for Particles and Surfaces........................................................................................ 5 Fundamentals Waters™ Premier Standards to Investigate the Inertness of Chromatographic Systems....................................................................................................................................7…