HANDLING THE NOTICEABLE NON-LINEARITY OF MASS CALIBRATION IN HIGH RESOLUTION TOF MS

EXAMINING THE M/Z SEPARATIVE CAPABILITY OF TRAVELLING WAVES FOR LARGE MOLECULE CHARACTERISATION Jakub Ujma,1 David Langridge,1 Keith Richardson,1 Kamila Pacholarz,2 Ellen Liggett,3 Jason Wildgoose,1 Perdita Barran,3 Ian Anderson,4 Kevin Giles,1 Malcolm Anderson1 1. Waters Corporation, Wilmslow, United Kingdom; 2. KP…

AS MS 2 0 2 5 , WP 3 3 7 Improving the AC-ejection method for enhanced duty cycle and wide m/z range detection of ions in oTOF-MS Introduction Orthogonal acceleration (OA) as a method for gating ions into a…

C10G-E073 WHITE PAPER On the Accurate Understanding of Mass Measurement Accuracy in Q-TOF MS High-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matrix and to allow identification of compounds by…

Time-of-Flight Mass Spectrometry Technical Overview John Fjeldsted Agilent Technologies Introduction Time-of-flight mass spectrometry (TOF MS) was developed in the late 1940’s, but until the 1990’s its popularity was limited. Recent improvements in TOF technology, including orthogonal acceleration, ion mirrors (reflectrons),…