Exploring the Impact of Part Per Billion Mass Accuracy for Metabolite Identification Using Multi Reflecting Time-of-Flight MS With UPLC™ Part A

Application Note Exploring the Impact of Part Per Billion Mass Accuracy for Metabolite Identification using Multi Reflecting Time of Flight MS with UPLC™ Part B Michael McCullagh, Martin Palmer, David Eatough, Emma Marsden-Edwards, James I. Langridge, Dale CooperShepherd Waters Corporation…

THE IMPACT of PPB MASS ACCURACY UPON BIOTRANSFORMATION PRODUCT IDENTIFICATION USING NEGATIVE ION NON -TARGETED URINARY SCREENING MULTI-REFLECTING TIME-OF-FLIGHT LCMS 1 1 Michael McCullagh, 2Iggy Kass, 1Emma Marsden-Edwards, 1David Eatough, 1Dale Cooper-Shepherd and 1Martin Palmer. Waters Corporation, Stamford Avenue, Altrincham…

DATA INDEPENDENT ANALYSIS EVOLUTION: EXPLORING THE USE OF HIGH RESOLVING POWER MULTIREFLECTING TIME-of-FLIGHT MASS SPECTROMETRY FOR METABOLITE IDENTIFICATION 1 Michael McCullagh, 2Stephen Griffin, 1Emma Marsden-Edwards, 1David Eatough, 1Dale Cooper-Shepherd and 1Martin Palmer. Waters Corporation, Stamford Avenue, Altrincham Road, Wilmslow, SK9…

[ PRODUCT SOLUTION ] UPLC with the SELECT SERIES™ MRT for Metabolite Identification INTRODUCTION The SELECT SERIES MRT (Figure 1) is a state-of-the-art hybrid quadrupole Multi Reflecting Time-of-Flight mass spectrometer. It provides a unique combination of ultra-high (200,000 FWHM) resolution,…