Winning The Last Battle Against Edman Degradation: Reliable Leucine/Iso-leucine Differentiation In Peptide Sequencing Using an Orbitrap Fusion Mass Spectrometer

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Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer Jie Qian,1 Keith A. Waddell, 2 Zhiqi Hao2 1 Thermo Fisher Scientific, Somerset, NJ, 2Thermo Fisher Scientific San Jose, CA Overview Results Purpose:…

Results: Fatty acids comprising the molecular phospholipid species were unambiguously identified. ne Proteome Discoverer software is a node-based workflow engine and study management 55 platform for analysis of mass spectrometry-based proteomics datasets. The latest released version 2.1 fully supports isotopically-labeled…