Lipid Nanoparticle Analysis: Leveraging MS to Reduce Risk

Lipid Nanoparticle Impurity Monitoring Using Single Quadrupole Mass Detection for Regulated Environments Authors: Duanduan Han, Kellen DeLaney, Robert E. Birdsall, Ying Qing Yu Affiliation: Waters Corporation, Milford, MA Results Introduction Lipid Nanoparticles UV 3 AU 2 Cholesterol • Important for…

Application Note Characterizing and Monitoring Impurities in Lipid Nanoparticle Components Using the BioAccord™ LC-MS System with waters_connect™ Software Kellen DeLaney, Duanduan Han, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Lipid nanoparticles (LNP) have been used with high efficacy…

Application Note Optimized ELSD Workflow for Improved Detection of Lipid Nanoparticle Components Kellen DeLaney, Duanduan Han, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Gene and nucleic acid-based therapeutics have received notable attention in recent years. In order for…

Application Note Automating Charged Aerosol Detection (CAD) Analysis with Empower™ CDS Using a Single-Vendor Integrated LC Platform Robert Birdsall, Xiangsha Du, Pawel Bigos, Duanduan Han, Nikhil Bhiwankar Waters Corporation, United States Published on April 05, 2026 Abstract This app note…