Analysis of residual moisture in a lyophilized pharmaceutical product by near-infrared spectroscopy

Application Note: 50911 Near-Infrared Analysis of Critical Parameters in Lyophilized Materials Jeffrey Hirsch, Thermo Fisher Scientific, Madison, WI, USA Abstract Key Words • Antaris • FT-NIR • Lyophilization • Moisture • Thrombin Lyophilized materials are challenging samples for QA/QC measurement…

Application note Determination of moisture content in freeze-dried materials by FT-NIR spectroscopy Abstract Keywords The feasibility of Fourier transform near-infrared spectroscopy (FT-NIR) for Antaris, FT-NIR, integrating the determination of moisture in lyophilized preparation of folinic acid calcium salt sphere, lyophilization,…

Near-Infrared Spectroscopy Application Note NIR–21 Monitoring the purity of recovered solvents by NIRS The purity of a solvent (dichloromethane/methylene chloride) is monitored by NIR spectroscopy along with two of the major impurities (methanol and water). Method description Introduction The solvents…

Application Bulletin 410 Analysis of pharmaceuticals using near-infrared spectroscopy Branch Pharmaceuticals No. 5: Distinguishing between samples of the nucleic acid, deoxycytidine, which differed only in linker compound ......... 5 No. 6: Qualitative study of amino acids and amino acid salts…