Incorporation of an Automated Scoring Metric for High-Resolution/Accurate-Mass Targeted Peptide Quantitation Routine

APPLICATION NOTE 72916 A high-resolution accurate mass multi-attribute method for critical quality attribute monitoring and new peak detection Authors Haichuan Liu1, Royston Quintyn2, John Rontree3 Thermo Fisher Scientific 1 San Jose, CA 2 West Palm Beach, FL 3 Hemel Hempstead,…

Technical note | 004024 Leveraging Adaptive RT on the Orbitrap Ascend MultiOmics Tribrid mass spectrometer for improved sensitivity and throughput in targeted workflows Authors Goal Jingjing Huang, Philip Remes, To utilize the Adaptive RT feature on the Thermo Scientific™ Orbitrap™…

Improving Label-Free Quantification of Plasma and Serum Proteins Using a High-Resolution Hybrid Orbitrap Mass Spectrometer Maryann S. Vogelsang,1 Amol Prakash,1 David Sarracino,1 Scott Peterman,1 Bryan Krastins,1 Jennifer Sutton,1 Gregory Byram,1 Gouri Vadali,1 Shadab Ahmad,1 Bruno Darbouret, 2 Mary F. Lopez1…

Scott Peterman1, Kwasi Antwi2, Bryan Krastins1, Eric E. Niederkofler2, and Mary Lopez1 Thermo Fisher Scientific BRIMS, Cambridge, MA 2 Thermo Fisher Scientific, Tempe, AZ 1 Key Words Q Exactive, insulin, insulin variants, Pinpoint, HRAM, high resolution, accurate mass, MSIA, mass…