Thermo UltiMate 3000 Titanium System

Application Note 127 Monitoring Monoclonal Antibody Heterogeneity by Cation-Exchange Chromatography INTRODUCTION During the development and production of therapeutic proteins, characterization of structural variants is a critical challenge. C-terminal processing of lysine residues on the heavy chain of monoclonal antibodies (MAbs)…

Application Note 125 Monitoring Protein Deamidation by Cation-Exchange Chromatography Introduction A common structural modification of recombinant proteins is the deamidation of asparagine (Asn) residues.1,2 This modification occurs in a variety of protein-based pharmaceuticals, including human growth hormone, tissue plasminogen activator,…

C H R O M ATO G R A P H Y The Benchmark in LC Liquid Handling Thermo Scientific™ Dionex™ UltiMate™ 3000 products are UHPLC compatible by design, establishing the new standard in conventional LC. Integrating hardware, software, and…

C H R O M ATO G R A P H Y The Benchmark in LC Solvent Delivery Produ c t Spe ci f i cat i ons Thermo Scientific Dionex UltiMate 3000 Pumps Thermo Scientific™ Dionex™ UltiMate™ 3000 products…