Rapid UHPLC Analysis of Natural DNA (12 mer) and its Impurities

LCMS-2050 Liquid Chromatograph Mass Spectrometer Application News Qualitative Analysis of Synthetic DNA Using a Single Quadrupole Mass Spectrometer Junna Nakazono User Benefits  Oligonucleotides can be easily analyzed using a Nexera™ XS inert UHPLC system and an LCMS-2050 single quadrupole…

ERAS-1000-0584 LC-MS Reversed-phase Shim-packTM Series Shim-pack ScepterTM Claris C18-120 584 Analysis of Synthetic DNA Keywords: Oligonucleotides, pharmaceuticals 1. Synthetic DNA [HPLC conditions] (NexeraTM XS inert) Column : Shim-pack Scepter Claris C18-120, 100 mm x 2.1 mm I.D., 1.9 µm*1 Flow…

ERAS-1000-0235 LC Reversed-phase Shim-packTM Series Shim-pack ScepterTM C18-120 Analysis of Phosphorothioate Oligonucleotides 235 Keywords: antisense oligonucleotides Mipomersen-2’-deoxy: 5'-mG-mC*-mC*-mU*-mC*-dA-dGdT-dC*-dT-dG-dC*-dT-dT-dC*-mGmC*-mA-mC*-mC*-3 System Column Mobile phase Time program Flow rate Column temp. Injection volume : NexeraTM / LCMSTM-9030 : Shim-pack Scepter C18-120 (75 mm…

Biopharma / LCMSTM-9030 Application News Ion-Pair Reversed-Phase (IP-RP) LCMS-9030 (Q-TOF) Mass Spectrometer for Separation and Identification of Oligonucleotides Yonghai Lu, Zhaoqi Zhan User Benefits  High-resolution separation of 10 to 60 base oligonucleotides using an ion-pairing buffer system  High-accuracy…