Agilent Biocolumns - Aggregate/Fragment Analysis - Application Compendium

Application Note Biotherapeutics and Biosimilars Analysis of Covalent High Molecular Weight Insulin Improvements in speed and resolution with high performance size exclusion chromatography Author Sandeep Kondaveeti Agilent Technologies, Inc. Abstract The analysis of insulin was done with an HPLC size…

Agilent Biocolumns Critical Quality Attributes Application Compendium Contents Introduction 05 1 Titer determination 07 1.1 1.2 1.3 1.4 1.5 Background Getting Started How to Guide - Affinity Chromatography for Titer Determination Featured Application Notes Cell Clone Selection Using the Agilent…

Application Note Pharma and Biopharma SEC Method Transfer from Diol Chemistry to Polymer-Coated Silica Author Richard Hurteau Agilent Technologies, Inc. Abstract The Agilent AdvanceBio SEC 130 and 300 Å columns contain highly uniform, 2.7-µm particles, with a low-binding, polymer-coated silica…

Application Note Biopharma High Resolution Size Exclusion Chromatography Analysis of Small Therapeutic Proteins Authors Sandeep Kondaveeti, Te‑Wei Chu, and Andrew Coffey Agilent Technologies, Inc. Abstract Protein denaturation processes involving aggregation are among the factors impeding the development of stable protein…