Fast and Efficient Peptide Mapping of a Monoclonal Antibody (mAb): UHPLC Performance with Superficially Porous Particles

AdvanceBio Peptide Mapping An HPLC Column Technology for Faster Protein Biocharacterizations Tim Rice BioColumn Technical Specialist 1 September 10, 2014 What Is Peptide Mapping? • The chemical or enzymatic treatment of a protein to produce peptide fragments • Separation and…

Agilent-NISTmAb Peptide Mapping Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge variants…

Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM Application Note Biotherapeutics and Biosimilars Author Introduction Suresh Babu C.V. Post-translational modifications (PTMs) on proteins such as monoclonal antibodies (mAbs) are critical quality attributes (CQAs) that define the…

High Resolution and Rapid Peptide Mapping of Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC and an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Authors Introduction Ning Tang Peptide mapping is the common analytical technique for characterizing biologic therapeutic…