Intact Protein Analysis Using an Agilent 6550 Q-TOF Mass Spectrometer

Precise Characterization of Intact Monoclonal Antibodies by the Agilent 6545XT AdvanceBio LC/Q-TOF Application Note Author Introduction David L. Wong Monoclonal antibodies (mAbs) are a very important class of biopharmaceutical molecules. As a protein drug, thorough characterization of the mAb is…

Analysis of Monoclonal Antibody (mAb) Using Agilent 1290 Infinity LC System Coupled to Agilent 6530 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) Application Note Authors Abstract Ravindra Gudihal and Suresh Babu CV This Application Note describes the use of an Agilent 1290 Infinity…

Application Note Biologics Efficient Monoclonal Antibody and Antibody Drug Conjugate Desalting Prior to Mass Spectrometry Using AdvanceBio Desalting-RP Cartridges Authors Isabel Vandenheede, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) President Kennedypark 26 B-8500 Kortrijk Anne Blackwell and…

Application Note Pharma & Biopharma Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS Author David L. Wong Agilent Technologies, Inc. Abstract Native mass spectrometry can be used for a variety of protein-based applications, such as protein-protein interaction, protein-ligand…