Organ transplantationplantation

Standardization of LC-MS for Therapeutic Drug Monitoring of Tacrolimus Thomas Annesley,1 Denise McKeown,2 David Holt,3 Christopher Mussell,4 Elodie Champarnaud,4 Leonie Harter,5 Lisa Calton,5 and Donald Mason6 1 University of Michigan, Ann Arbor, MI; 2University of Glasgow, Glasgow, UK; 3Analytical Services…

® DOSIMMUNE : Fully automated analysis of immunosuppressant drugs in whole blood using stable isotope labeled internal standards Fanny Dayot1, Jean-François Hoeffler1, Toshikazu Minohata1,2 1 ALSACHIM SAS, Illkirch, France, 2 Shimadzu Corporation, Kyoto, Japan 1. Introduction 3. Result and discussion…

White paper Reducing risk in HPLC / LC-MS therapeutic drug treatment and monitoring Why water purity matters WATER TECHNOLOGIES 2 Dedicated to Discovery Inside 4 Introduction 5 i LC-MS/MS for therapeutic drug monitoring (TDM) and treatment 8 ii UHPLC-MS/MS method…

Application Note Clinical Research Ultrafast Quantitation of Immunosuppressant Drugs in Whole Blood by Agilent 6475 LC/MS Author Udi Jumhawan Agilent Technologies, Inc. Abstract An ultrafast, 2.5-minute quantitation method using liquid chromatography/mass spectrometry (LC/MS) for four immunosuppressant drugs was established using…