Performance of ACQUITY UPLC M-Class in Proteomics Nanoscale Applications

Advancing Host Cell Protein Analyses Through the Combined Use of Microscale 2D RP/RP with CSH C18 and Ion Mobility Enabled MS Detection Matthew A. Lauber, Catalin E. Doneanu, Stephan M. Koza, Weibin Chen, and Kenneth J. Fountain Waters Corporation, Milford,…

[ TECHNOLOGY BRIEF ] Characteristics of Proteomics Experiments Performed on the SYNAPT XS Q-ToF Mass Spectrometer Christopher Hughes and Lee Gethings Waters Corporation, Wilmslow, United Kingdom SYNAPT XS and ACQUITY UPLC M-Class with nanoscale chromatography enhances resolution and sensitivity, as…

Assay for Identification and Quantification of Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm: An Inter-Laboratory Study Catalin E. Doneanu, Malcolm Anderson, Brad J. Williams, Matthew A. Lauber, Asish Chakraborty, and Weibin Chen Waters Corporation, Milford,…

Application Note MaxPeak High Performance Surfaces Enable Reproducibility and Enhanced Experimental Robustness in High Throughput Proteomics Chris Hughes, Lee A. Gethings, Robert S. Plumb Waters Corporation Abstract Robust and reproducible LC-MS is an essential requirement in large scale clinical proteomic…