A Label-free, Multi-omic Study to Qualitatively and Quantitatively Characterize the Effects of a Glucosylceramide Inhibitor on Obesity

A LABEL-FREE, MULTI-OMIC STUDY TO QUALITATIVELY AND QUANTITATIVELY CHARACTERIZE THE EFFECTS OF A GLUCOSYLCERAMIDE INHIBITOR ON OBESITY Gertjan Kramer1, Nicholas Dekker1, Lee A Gethings2, John P Shockcor3, Victoria Lee4, Robert J. Beynon4, Robert Tonge2, James I Langridge2, Johannes PC Vissers2,…

[ APPLICATION NOTE ] A Multi-omic Approach for the Study of Heart Regeneration Using Zebrafish as a Model Organism Leanne Nye, 1,2 Lee A. Gethings, 2 Shuk Han Cheng, 3 Yun Wah Lam, 3 Fatemah Babei, 3 Alfred W. H…

[ APPLICATION NOTE ] Biological Interpretation of Breast Cancer Using Rapid Multi-omic Profiling Methods Adam King, Christopher J. Hughes, Giorgis Isaac, Lee A. Gethings, and Robert S. Plumb Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ ■ Flexible, multi-omic…

[ APPLICATION NOTEBOOK ] UNTARGETED METABOLOMICS AND LIPIDOMICS 1 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Development of a Metabolomic Assay for the Analysis…