Automating the Determination of Drug-to-Antibody Ratio (DAR) of Antibody Drug Conjugates (ADCs) Based on Separation by Hydrophobic Interaction Chromatography (HIC) Robert Birdsall, Eoin Cosgrave, Henry Shion, and Weibin Chen Waters Corporation, Milford, MA, USA A P P L I C…
Klíčová slova
dar, antibody, adcs, drug, conjugates, automating, calculations, ratio, cqas, uplc, acquity, hic, conjugated, determination, cysteine