High Sensitivity Bioanalysis for Small Drug-Like Compounds in Human Plasma using Microflow LC and High Resolution Mass Spectrometry

Exploring Extra Sensitivity Using ionKey/MS with the Xevo G2-XS QTof HRMS for Small Molecule Pharmaceutical Analysis in Human Plasma Yun Wang Alelyunas, Mark D. Wrona, Jim Murphy, Angela Doneanu, Gregory Roman, and Paul Rainville Waters Corporation, Milford, MA, USA A…

[ ion key / MS ] APPLICATION COMPENDIUM Dear Colleague, The 2014 introduction of the ionKey/MS System was a turning point for LC-MS. The promise of increased levels of sensitivity from smaller sample sizes was finally a reality. We were…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…

[ TECHNOLOGY BRIEF ] Increasing Throughput for the Analysis of Human Insulin and Related Biotherapeutic Analogs using the ionKey/MS System Michael Donegan, James Murphy, and Erin Chambers Waters Corporation, Milford, MA, USA The ionKey/MS System enables the flexibility to modulate…