Orthogonal Detection Techniques to Provide More Complete Characterization of an Oral Drug

Application Note Separation and Detection of an Azido Impurity in Sartan Drug Substances Using the XSelect CSH Phenyl-Hexyl Column by UHPLC-UV-MS Kenneth D. Berthelette, Jennifer M. Nguyen, Mary Trudeau, Jonathan E. Turner Waters Corporation Abstract Recent genotoxic impurity concerns around…

Repeatability and Quantitation in a Method Using the Alliance HPLC System with the 2998 Photodiode Array Detector and the ACQUITY QDa Detector Aparna Chavali, Thomas E. Wheat, Patricia McConville Waters Corporation, Milford, MA, USA A P P L I C…

Application Note Analytical Quality by Design Based Method Development for the Analysis of Valsartan and Nitrosamines Impurities Using UPLCMS Fadi L. Alkhateeb, Paul D. Rainville Waters Corporation Abstract An UltraPerformance Liquid Chromatography method is developed for the analysis of Valsartan…

Routine MS Detection for USP Chromatographic Methods Daniel S. Root, Thomas E. Wheat, and Patricia McConville Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N E F I T S INT…