Agilent Hybrid SFC/UHPLC-Triple Quadrupole System for Achiral and Chiral Metabolite Analysis

Investigating the Chiral Metabolism of an Achiral Drug Using Agilent SFC‑MS/MS Technology Application Note Pharma Discovery Authors Abstract Siji Joseph A robust SFC-MS/MS method was developed for the quantification of achiral Agilent Technologies, Inc. risperidone and its enantiomeric hydroxy metabolite.…

Agilent LC/Q-TOF and Mass MetaSite Software for Seamless Metabolite Identification Application Note Small Molecule Pharmaceuticals Author Abstract Siji Joseph The detection and identification of metabolites is a critical step in the early drug Application Scientist discovery phase. The identification of…

Fast Analysis of Chiral and Structurally Related Isomers Using Supercritical Fluid Chromatography Mass Spectrometry Application Note Authors Abstract Yuqin Dai and Lisa Zang This Application Note demonstrates the use of Agilent 1260 Infinity Analytical Agilent Technologies, Inc. Supercritical Fluid Chromatography…

Introducing automated online multicolumn twodimensional liquid chromatography screening as a rapid and efficient tool for method development of multiple pipeline modalities Heather Wang, Zach Dunn, Andrew Singh, Rodell Barrientos; Hayley R. Lhotka, Imad A. Haidar Ahmad, Erik L. Regalado, Multidimensional…