High-throughput Screening of Oligonucleotides for Identity and Purity Assessment Using the ACQUITY QDa Detector and ProMass for MassLynx Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA A P P L I C AT I O N…
[ APPLICATION NOTE ] Developing a Novel, Integrated LC-MS Workflow for High-resolution Monitoring and Characterization of Oligonucleotides Henry Shion, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Optimized RP-UPLC mobile phase Methods that…
[ APPLICATION NOTE ] Evaluation of Alternative Ion-pairing Reagents in the Analysis of Oligonucleotides with the ACQUITY QDa Detector Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Method compatibility with alternative Electrospray…
ADDING COST EFFECTIVE MASS DETECTION FOR IMPROVED PRODUCTIVITY IN OLIGONUCLEOTIDE SCREENING ASSAYS Robert E. Birdsall, Sean M. McCarthy, Scott J. Berger, Maki Terasaki, Kenji Hiroseand Ying Qing Yu Biopharmaceutical Business Team, Waters Corporation, Milford, MA and Tokyo, Japan TUV Absorbance…
