Analysis of Genotoxic Impurities of Imatinib Mesylate by LC-MS from Early Development to Routine Monitoring

Coupling Mass Detection with UV to Improve Method Sensitivity for Esters of Benzenesulfonic Acid in Analysis of Genotoxic Impurities Margaret Maziarz and Mark Wrona Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…

[ BROCHURE ] SUPPORTING THE CHALLENGE OF NITROSAMINE DRUG SUBSTANCE RELATED IMPURITIES ANALYSIS N-Nitrosamines are potentially mutagenic impurities that may pose a risk of cancer to humans when exposed over a prolonged period. Since 2018, global regulatory bodies have required…

RADAR and PICS Compendium RADAR and PICS Compendium [ TABLE OF CONTENTS ] PAGE RADAR PICs RADAR and PICs CHEMICAL MATERIALS 5 Enantioseparation and Detection of Triazole Fungicides in Wheat Grain and Wheat Straw using the ACQUITY UPC2 System and…

The Use of the ACQUITY QDa Detector for a Selective, Sensitive, and Robust Quantitative Method for a Potential Genotoxic Impurity Janet Hammond Waters Corporation, Wilmslow, UK A P P L I C AT I O N B E N E…