A Comparative Study Using Preparative Reverse Phase Liquid Chromatography and Supercritical Fluid Chromatography of Impurities from a Stressed Pharmaceutical Drug Substance

[ APPLICATION NOTE ] Mass Directed SFC Purification Using ACQUITY QDa: Torus 2-PIC Separation of Goldenseal Alkaloids Kenneth D. Berthelette and Thomas Swann Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Prep SFC-MS method for mass-directed Natural products…

[ APPLICATION NOTE ] The Use of ACQUITY UPC2 and the Waters SFC Investigator System for the Analysis, Separation, and Isolation of Canagliflozin and Two Isomeric Impurities Arghya Acharjee, 1 Dilshad Pullancheri,1 Bronsky Gopinadh, 1 Anil Kurup, 1 Dr. Padmakar…

[ CARE AND USE MANUAL ] Torus Columns CONT ENT S I. INT RODUC T ION II. G E T T ING STA RT E D a. Safety Considerations b. Column Connectors and Installation c. Column Equilibration d. eCord Installation…

Improving Productivity in Purifying Antroquinonol Using UltraPerformance Convergence Chromatography (UPC 2) and Preparative Supercritical Fluid Chromatography (Prep SFC) Rui Chen,1 John McCauley,1 Jo-Ann Jablonski,1 Carol Fang,2 and Jacquelyn Runco1 1 Waters Corporation, Milford, MA, USA 2 Waters Taiwan, Taipei City,…